Algeria Angola Argentina Australia Bahrain Bangladesh Botswana Brazil Cameroon Canada Chile China Colombia Congo, Dem Rep of Cote d'Ivoire Egypt Ethiopia France Gabon Germany Ghana Hong Kong India Indonesia Iraq Ireland Italy Japan Jordan Kenya Kuwait Lebanon Libya Macao Malaysia Mali Mauritius Mexico Morocco Mozambique Namibia Netherlands New Zealand Nigeria Oman Pakistan Palestine Philippines Poland Portugal Qatar Rwanda Saudi Arabia Senegal Singapore South Africa South Korea Spain Sri Lanka Sudan Sweden Switzerland

Taiwan Tanzania Thailand Tunisia Turkey Uganda United Arab Emirates United Kingdom United States Vietnam Zambia Zimbabwe Deutsch English Français Italiano

Fare Guide

Estimated lowest fares found within 7 days

The cheapest airline(s) flying from Madrid to Santa Cruz de la Sierra is Boliviana De Aviacion.

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Madrid to Santa Cruz de la Sierra is May.

Jan 2025
Feb 2025
Mar 2025
Apr 2025
May 2025
Jun 2025
Jul 2025
Aug 2025
Sep 2025
Oct 2025
Nov 2025
Dec 2025

The cheapest day(s) of the week to fly from Madrid to Santa Cruz de la Sierra is Friday.

Sun Sunday
Mon Monday
Tue Tuesday
Wed Wednesday
Thu Thursday
Fri Friday
Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
- Latest
Duration
- Shortest
- Longest
Stopover
All
Airline Filter by Airline
View All Airline
Availability
- M
- T
- W
- T
- F
- S
- S

13:45 MAD

19:45 VVI

11Hrs, 00m Direct
MADMadrid Barajas Airport 13:45 - VVI 19:45 11h Direct
MADMadrid Barajas Airport 13:45
VVISanta Cruz Viru Viru International Airport 19:45
11h
Direct
Boliviana De Aviacion (OB 773)Airbus Industrie A330 200
Boliviana De Aviacion (OB 773)
- M
- -
- W
- -
- -
- S
- -
Airbus Industrie A330 200

21:30 MAD

04:00 VVI

11Hrs, 30m Direct
MADMadrid Barajas Airport 21:30 - VVI 04:00 11h 30m Direct
MADMadrid Barajas Airport 21:30
VVISanta Cruz Viru Viru International Airport 04:00
11h 30m
Direct
Boliviana De Aviacion (OB 777)Airbus Industrie A330 200
Boliviana De Aviacion (OB 777)
- -
- -
- -
- -
- F
- -
- S
Airbus Industrie A330 200

23:35 MAD

05:55 VVI

11Hrs, 20m Direct
MADMadrid Barajas Airport 23:35 - VVI 05:55 11h 20m Direct
MADMadrid Barajas Airport 23:35
VVISanta Cruz Viru Viru International Airport 05:55
11h 20m
Direct
Air Europa (UX 25)Boeing 787 9
Air Europa (UX 25)
- -
- -
- W
- -
- -
- -
- S
Boeing 787 9

23:35 MAD

05:55 VVI

11Hrs, 20m Direct
MADMadrid Barajas Airport 23:35 - VVI 05:55 11h 20m Direct
MADMadrid Barajas Airport 23:35
VVISanta Cruz Viru Viru International Airport 05:55
11h 20m
Direct
Air Europa (UX 25)Boeing 787
Air Europa (UX 25)
- M
- -
- -
- -
- -
- -
- -
Boeing 787

10:55 MAD

02:00 VVI

20Hrs, 05m 1 Stop (BOG)
MADMadrid Barajas Airport 10:55 - VVI 02:00 20h 05m 1 Stop (BOG) Bogota
MADMadrid Barajas Airport 10:55

BOGBogota Airport 20:55
BOGBogota Airport 15:20

VVISanta Cruz Viru Viru International Airport 02:00
20h 05m (5h 35m)
1 Stop BOG · Bogota 5h 35m
Avianca (AV 183)Boeing 787 8

Avianca (AV 8382)Airbus
Avianca (AV 183)
- M
- -
- W
- -
- -
- -
- S

10:55 MAD

02:00 VVI

20Hrs, 05m 1 Stop (BOG)
MADMadrid Barajas Airport 10:55 - VVI 02:00 20h 05m 1 Stop (BOG) Bogota
MADMadrid Barajas Airport 10:55

BOGBogota Airport 20:55
BOGBogota Airport 15:20

VVISanta Cruz Viru Viru International Airport 02:00
20h 05m (5h 35m)
1 Stop BOG · Bogota 5h 35m
Avianca (AV 183)Boeing 787 8

Avianca (AV 8382)Airbus
Avianca (AV 183)
- -
- -
- -
- T
- F
- S
- -

11:45 MAD

03:36 VVI

20Hrs, 51m 1 Stop (PTY)
MADMadrid Barajas Airport 11:45 - VVI 03:36 20h 51m 1 Stop (PTY) Panama City
MADMadrid Barajas Airport 11:45

PTYPanama City Tocumen International Airport 21:43
PTYPanama City Tocumen International Airport 16:50

VVISanta Cruz Viru Viru International Airport 03:36
20h 51m (4h 53m)
1 Stop PTY · Panama City 4h 53m
Iberia (IB 257)Airbus

Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
Iberia (IB 257)
- -
- -
- W
- -
- -
- -
- -

11:45 MAD

03:36 VVI

20Hrs, 51m 1 Stop (PTY)
MADMadrid Barajas Airport 11:45 - VVI 03:36 20h 51m 1 Stop (PTY) Panama City
MADMadrid Barajas Airport 11:45

PTYPanama City Tocumen International Airport 21:43
PTYPanama City Tocumen International Airport 16:50

VVISanta Cruz Viru Viru International Airport 03:36
20h 51m (4h 53m)
1 Stop PTY · Panama City 4h 53m
Iberia (IB 257)Airbus Industrie A330 200

Copa Airlines (CM 221)Boeing 737 800
Iberia (IB 257)
- -
- -
- -
- -
- F
- -
- -

11:45 MAD

03:36 VVI

20Hrs, 51m 1 Stop (PTY)
MADMadrid Barajas Airport 11:45 - VVI 03:36 20h 51m 1 Stop (PTY) Panama City
MADMadrid Barajas Airport 11:45

PTYPanama City Tocumen International Airport 21:43
PTYPanama City Tocumen International Airport 16:50

VVISanta Cruz Viru Viru International Airport 03:36
20h 51m (4h 53m)
1 Stop PTY · Panama City 4h 53m
Iberia (IB 257)Airbus Industrie A330 200

Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
Iberia (IB 257)
- -
- -
- -
- -
- -
- -
- S

13:10 MAD

04:45 VVI

20Hrs, 35m 1 Stop (LIM)
MADMadrid Barajas Airport 13:10 - VVI 04:45 20h 35m 1 Stop (LIM) Lima
MADMadrid Barajas Airport 13:10

LIMLima Airport 01:00
LIMLima Airport 19:10

VVISanta Cruz Viru Viru International Airport 04:45
20h 35m (5h 50m)
1 Stop LIM · Lima 5h 50m
Iberia (IB 125)Airbus A350

LATAM Airlines Group SA (LA 2406)Airbus
Iberia (IB 125)
- M
- T
- -
- -
- -
- -
- -

13:10 MAD

04:45 VVI

20Hrs, 35m 1 Stop (LIM)
MADMadrid Barajas Airport 13:10 - VVI 04:45 20h 35m 1 Stop (LIM) Lima
MADMadrid Barajas Airport 13:10

LIMLima Airport 01:00
LIMLima Airport 19:10

VVISanta Cruz Viru Viru International Airport 04:45
20h 35m (5h 50m)
1 Stop LIM · Lima 5h 50m
Iberia (IB 125)Airbus A359

LATAM Airlines Group SA (LA 2406)Airbus
Iberia (IB 125)
- -
- -
- W
- -
- F
- S
- S

15:10 MAD

03:36 VVI

17Hrs, 26m 1 Stop (PTY)
MADMadrid Barajas Airport 15:10 - VVI 03:36 17h 26m 1 Stop (PTY) Panama City
MADMadrid Barajas Airport 15:10

PTYPanama City Tocumen International Airport 21:43
PTYPanama City Tocumen International Airport 19:45

VVISanta Cruz Viru Viru International Airport 03:36
17h 26m (1h 58m)
1 Stop PTY · Panama City 1h 58m
Air Europa (UX 55)Boeing 787 8

Copa Airlines (CM 221)Boeing 737 Max 9 Passenger
Air Europa (UX 55)
- M
- -
- -
- -
- -
- -
- S

15:10 MAD

03:36 VVI

17Hrs, 26m 1 Stop (PTY)
MADMadrid Barajas Airport 15:10 - VVI 03:36 17h 26m 1 Stop (PTY) Panama City
MADMadrid Barajas Airport 15:10

PTYPanama City Tocumen International Airport 21:43
PTYPanama City Tocumen International Airport 19:45

VVISanta Cruz Viru Viru International Airport 03:36
17h 26m (1h 58m)
1 Stop PTY · Panama City 1h 58m
Air Europa (UX 55)Boeing 787 9

Copa Airlines (CM 221)Boeing 737 800
Air Europa (UX 55)
- -
- -
- -
- -
- F
- -
- -

21:30 MAD

06:40 VVI

14Hrs, 10m 1 Stop (CBB)
MADMadrid Barajas Airport 21:30 - VVI 06:40 14h 10m 1 Stop (CBB) Cochabamba
MADMadrid Barajas Airport 21:30

CBBCochabamba Airport 05:50
CBBCochabamba Airport 04:00

VVISanta Cruz Viru Viru International Airport 06:40
14h 10m (1h 50m)
1 Stop CBB · Cochabamba 1h 50m
Boliviana De Aviacion (OB 779)Airbus Industrie A330 200

Boliviana De Aviacion (OB 630)Boeing 737 300
Boliviana De Aviacion (OB 779)
- -
- T
- -
- -
- -
- -
- -

21:30 MAD

07:10 VVI

14Hrs, 40m 1 Stop (CBB)
MADMadrid Barajas Airport 21:30 - VVI 07:10 14h 40m 1 Stop (CBB) Cochabamba
MADMadrid Barajas Airport 21:30

CBBCochabamba Airport 06:20
CBBCochabamba Airport 04:00

VVISanta Cruz Viru Viru International Airport 07:10
14h 40m (2h 20m)
1 Stop CBB · Cochabamba 2h 20m
Boliviana De Aviacion (OB 779)Airbus Industrie A330 200

Boliviana De Aviacion (OB 632)Boeing 737 300
Boliviana De Aviacion (OB 779)
- -
- T
- -
- -
- -
- -
- -

07:25 LPB

04:00 CBB

16Hrs, 00m 1 Stop (VVI)
LPBLa Paz Airport 07:25 - CBB 04:00 16h 1 Stop (VVI) Santa Cruz de la Sierra
LPBLa Paz Airport 07:25

MADMadrid Barajas Airport 21:30
VVISanta Cruz Viru Viru International Airport 08:30

CBBCochabamba Airport 04:00
16h (2h 40m)
1 Stop VVI · Santa Cruz de la Sierra 2h 40m
Boliviana De Aviacion (OB 662)Boeing 737 800

Boliviana De Aviacion (OB 779)Airbus Industrie A330 200
Boliviana De Aviacion (OB 662)
- -
- T
- -
- -
- -
- -
- -

11:30 ASU

05:15 GRU

18Hrs, 35m 1 Stop (VVI)
ASUAsuncion Airport 11:30 - GRU 05:15 18h 35m 1 Stop (VVI) Santa Cruz de la Sierra
ASUAsuncion Airport 11:30

MADMadrid Barajas Airport 22:40
VVISanta Cruz Viru Viru International Airport 12:15

GRUSao Paulo Guarulhos Intl Airport 05:15
18h 35m (4h 10m)
1 Stop VVI · Santa Cruz de la Sierra 4h 10m
Paranair (ZP 862)Canadian Regional 200

LATAM Airlines Group SA (LA 715)Boeing 787 9
Paranair (ZP 862)
- -
- -
- -
- T
- -
- -
- S

14:05 ASU

07:05 GRU

19Hrs, 55m 1 Stop (VVI)
ASUAsuncion Airport 14:05 - GRU 07:05 19h 55m 1 Stop (VVI) Santa Cruz de la Sierra
ASUAsuncion Airport 14:05

MADMadrid Barajas Airport 23:55
VVISanta Cruz Viru Viru International Airport 14:50

GRUSao Paulo Guarulhos Intl Airport 07:05
19h 55m (4h 50m)
1 Stop VVI · Santa Cruz de la Sierra 4h 50m
Paranair (ZP 862)Canadian Regional 200

Iberia (IB 267)Airbus Industrie A330 200
Paranair (ZP 862)
- -
- -
- -
- -
- -
- S
- -

Sorry, there are no schedules matching your filters. Try removing one. reset

What’s the fastest flight time from Madrid to Santa Cruz de la Sierra?

The fastest flight time for direct flights from Madrid to Santa Cruz de la Sierra is 11 hours . Check latest flight schedules & prices on Wego.

How far is Santa Cruz de la Sierra from Madrid?

The flight distance between Madrid and Santa Cruz de la Sierra is 8919km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 07:25. The last flight of the day departs at 10:55. See the full list of flight times on Wego.

How many airlines offer direct flights from Madrid to Santa Cruz de la Sierra?

There are 2 airlines that offer direct flights from Madrid to Santa Cruz de la Sierra. Find out the list of airlines on Wego.

Popular Destinations From Santa Cruz de la Sierra

Popular Destinations From Madrid

Popular Hotels in Santa Cruz de la Sierra

Hotels In Popular Destinations

Wego searches for the best deals on these sites & many more