Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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      • Availability
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      • 06:55 TYS
        08:00 ORD
        2Hrs, 05m Direct
      • TYSKnoxville Airport 06:55 - ORD 08:00 2h 05m Direct
      • TYSKnoxville Airport 06:55
      • ORDChicago O'Hare International Airport 08:00
      • 2h 05m
      • Direct
      • United Airlines (UA 5281)Crj 700 Canadair Regional
      • United Airlines (UA 5281)
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      • Crj 700 Canadair Regional
      • 06:55 TYS
        08:02 ORD
        2Hrs, 07m Direct
      • TYSKnoxville Airport 06:55 - ORD 08:02 2h 07m Direct
      • TYSKnoxville Airport 06:55
      • ORDChicago O'Hare International Airport 08:02
      • 2h 07m
      • Direct
      • United Airlines (UA 5281)Embraer 175
      • United Airlines (UA 5281)
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        • -
      • Embraer 175
      • 10:45 TYS
        11:52 ORD
        2Hrs, 07m Direct
      • TYSKnoxville Airport 10:45 - ORD 11:52 2h 07m Direct
      • TYSKnoxville Airport 10:45
      • ORDChicago O'Hare International Airport 11:52
      • 2h 07m
      • Direct
      • United Airlines (UA 5843)Canadair Regional Jet 550
      • United Airlines (UA 5843)
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      • Canadair Regional Jet 550
      • 11:39 TYS
        12:34 ORD
        1Hrs, 55m Direct
      • TYSKnoxville Airport 11:39 - ORD 12:34 1h 55m Direct
      • TYSKnoxville Airport 11:39
      • ORDChicago O'Hare International Airport 12:34
      • 1h 55m
      • Direct
      • American Airlines (AA 4595)Embraer Emb 175
      • American Airlines (AA 4595)
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      • Embraer Emb 175
      • 11:39 TYS
        12:34 ORD
        1Hrs, 55m Direct
      • TYSKnoxville Airport 11:39 - ORD 12:34 1h 55m Direct
      • TYSKnoxville Airport 11:39
      • ORDChicago O'Hare International Airport 12:34
      • 1h 55m
      • Direct
      • American Airlines (AA 3798)Embraer 170
      • American Airlines (AA 3798)
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        • -
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      • Embraer 170
      • 17:35 TYS
        18:38 ORD
        2Hrs, 03m Direct
      • TYSKnoxville Airport 17:35 - ORD 18:38 2h 03m Direct
      • TYSKnoxville Airport 17:35
      • ORDChicago O'Hare International Airport 18:38
      • 2h 03m
      • Direct
      • United Airlines (UA 5305)Embraer 175
      • United Airlines (UA 5305)
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      • Embraer 175
      • 18:12 TYS
        19:10 ORD
        1Hrs, 58m Direct
      • TYSKnoxville Airport 18:12 - ORD 19:10 1h 58m Direct
      • TYSKnoxville Airport 18:12
      • ORDChicago O'Hare International Airport 19:10
      • 1h 58m
      • Direct
      • American Airlines (AA 3899)Embraer Emb 175
      • American Airlines (AA 3899)
        • -
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        • -
      • Embraer Emb 175
      • 18:41 TYS
        19:39 ORD
        1Hrs, 58m Direct
      • TYSKnoxville Airport 18:41 - ORD 19:39 1h 58m Direct
      • TYSKnoxville Airport 18:41
      • ORDChicago O'Hare International Airport 19:39
      • 1h 58m
      • Direct
      • American Airlines (AA 3899)Embraer Emb 175
      • American Airlines (AA 3899)
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      • Embraer Emb 175
      • 19:24 TYS
        23:25 ORD
        5Hrs, 01m 1 Stop (IAD)
      • TYSKnoxville Airport 19:24 - ORD 23:25 5h 01m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 19:24
        IADWashington Dulles International Airport 22:20
      • IADWashington Dulles International Airport 21:10
        ORDChicago O'Hare International Airport 23:25
      • 5h 01m (1h 10m)
      • 1 Stop IAD · Washington 1h 10m
      • United Airlines (UA 4324)Embraer
        United Airlines (UA 1738)Boeing 757 200 Series
      • United Airlines (UA 4324)
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      • 05:00 TYS
        08:55 ORD
        4Hrs, 55m 1 Stop (CLT)
      • TYSKnoxville Airport 05:00 - ORD 08:55 4h 55m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 05:00
        CLTCharlotte Airport 07:44
      • CLTCharlotte Airport 06:27
        ORDChicago O'Hare International Airport 08:55
      • 4h 55m (1h 17m)
      • 1 Stop CLT · Charlotte 1h 17m
      • American Airlines (AA 5435)Canadair Regional
        American Airlines (AA 2843)Airbus
      • American Airlines (AA 5435)
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      • 05:45 TYS
        09:55 ORD
        5Hrs, 10m 1 Stop (IAD)
      • TYSKnoxville Airport 05:45 - ORD 09:55 5h 10m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 05:45
        IADWashington Dulles International Airport 08:35
      • IADWashington Dulles International Airport 07:29
        ORDChicago O'Hare International Airport 09:55
      • 5h 10m (1h 06m)
      • 1 Stop IAD · Washington 1h 06m
      • United Airlines (UA 4311)Embraer
        United Airlines (UA 1710)Airbus
      • United Airlines (UA 4311)
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      • 07:05 TYS
        11:01 ORD
        4Hrs, 56m 1 Stop (CLT)
      • TYSKnoxville Airport 07:05 - ORD 11:01 4h 56m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 07:05
        CLTCharlotte Airport 09:40
      • CLTCharlotte Airport 08:38
        ORDChicago O'Hare International Airport 11:01
      • 4h 56m (1h 02m)
      • 1 Stop CLT · Charlotte 1h 02m
      • American Airlines (AA 5087)Crj 700 Canadair Regional
        American Airlines (AA 1668)Boeing 737 Max 8 Passenger
      • American Airlines (AA 5087)
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      • 07:48 TYS
        12:15 ORD
        5Hrs, 27m 1 Stop (PHL)
      • TYSKnoxville Airport 07:48 - ORD 12:15 5h 27m 1 Stop (PHL) Philadelphia
      • TYSKnoxville Airport 07:48
        PHLPhiladelphia International Airport 10:41
      • PHLPhiladelphia International Airport 09:50
        ORDChicago O'Hare International Airport 12:15
      • 5h 27m (51m)
      • 1 Stop PHL · Philadelphia 51m
      • American Airlines (AA 5620)Canadair Regional
        American Airlines (AA 1920)Boeing 737 800
      • American Airlines (AA 5620)
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        • S
      • 09:08 TYS
        12:12 ORD
        4Hrs, 04m 1 Stop (CLT)
      • TYSKnoxville Airport 09:08 - ORD 12:12 4h 04m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 09:08
        CLTCharlotte Airport 11:01
      • CLTCharlotte Airport 10:25
        ORDChicago O'Hare International Airport 12:12
      • 4h 04m (36m)
      • 1 Stop CLT · Charlotte 36m
      • American Airlines (AA 5291)Canadair Regional
        American Airlines (AA 2279)Airbus A321 Neo
      • American Airlines (AA 5291)
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        • -
      • 09:50 TYS
        14:15 ORD
        5Hrs, 25m 1 Stop (IAD)
      • TYSKnoxville Airport 09:50 - ORD 14:15 5h 25m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 09:50
        IADWashington Dulles International Airport 12:55
      • IADWashington Dulles International Airport 11:36
        ORDChicago O'Hare International Airport 14:15
      • 5h 25m (1h 19m)
      • 1 Stop IAD · Washington 1h 19m
      • United Airlines (UA 4325)Embraer
        United Airlines (UA 1581)Airbus
      • United Airlines (UA 4325)
        • -
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        • -
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        • -
      • 09:50 TYS
        14:05 ORD
        5Hrs, 15m 1 Stop (IAD)
      • TYSKnoxville Airport 09:50 - ORD 14:05 5h 15m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 09:50
        IADWashington Dulles International Airport 12:45
      • IADWashington Dulles International Airport 11:36
        ORDChicago O'Hare International Airport 14:05
      • 5h 15m (1h 09m)
      • 1 Stop IAD · Washington 1h 09m
      • United Airlines (UA 4325)Embraer
        United Airlines (UA 1581)Boeing 737 700
      • United Airlines (UA 4325)
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      • 09:50 TYS
        14:05 ORD
        5Hrs, 15m 1 Stop (IAD)
      • TYSKnoxville Airport 09:50 - ORD 14:05 5h 15m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 09:50
        IADWashington Dulles International Airport 12:45
      • IADWashington Dulles International Airport 11:36
        ORDChicago O'Hare International Airport 14:05
      • 5h 15m (1h 09m)
      • 1 Stop IAD · Washington 1h 09m
      • United Airlines (UA 4325)Embraer
        United Airlines (UA 1581)Airbus
      • United Airlines (UA 4325)
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      • 09:50 TYS
        14:00 ORD
        5Hrs, 10m 1 Stop (IAD)
      • TYSKnoxville Airport 09:50 - ORD 14:00 5h 10m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 09:50
        IADWashington Dulles International Airport 12:40
      • IADWashington Dulles International Airport 11:36
        ORDChicago O'Hare International Airport 14:00
      • 5h 10m (1h 04m)
      • 1 Stop IAD · Washington 1h 04m
      • United Airlines (UA 4325)Embraer
        United Airlines (UA 1581)Airbus
      • United Airlines (UA 4325)
        • -
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        • -
        • -
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      • 10:55 TYS
        15:16 ORD
        5Hrs, 21m 1 Stop (PHL)
      • TYSKnoxville Airport 10:55 - ORD 15:16 5h 21m 1 Stop (PHL) Philadelphia
      • TYSKnoxville Airport 10:55
        PHLPhiladelphia International Airport 13:48
      • PHLPhiladelphia International Airport 12:49
        ORDChicago O'Hare International Airport 15:16
      • 5h 21m (59m)
      • 1 Stop PHL · Philadelphia 59m
      • American Airlines (AA 5867)Er4 Embraer Rj145 Amazon
        American Airlines (AA 470)Airbus
      • American Airlines (AA 5867)
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      • 10:55 TYS
        15:08 ORD
        5Hrs, 13m 1 Stop (PHL)
      • TYSKnoxville Airport 10:55 - ORD 15:08 5h 13m 1 Stop (PHL) Philadelphia
      • TYSKnoxville Airport 10:55
        PHLPhiladelphia International Airport 13:40
      • PHLPhiladelphia International Airport 12:49
        ORDChicago O'Hare International Airport 15:08
      • 5h 13m (51m)
      • 1 Stop PHL · Philadelphia 51m
      • American Airlines (AA 5867)Er4 Embraer Rj145 Amazon
        American Airlines (AA 470)Airbus
      • American Airlines (AA 5867)
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      • 10:58 TYS
        14:12 ORD
        4Hrs, 14m 1 Stop (CLT)
      • TYSKnoxville Airport 10:58 - ORD 14:12 4h 14m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 10:58
        CLTCharlotte Airport 13:04
      • CLTCharlotte Airport 12:08
        ORDChicago O'Hare International Airport 14:12
      • 4h 14m (56m)
      • 1 Stop CLT · Charlotte 56m
      • American Airlines (AA 3272)Airbus
        American Airlines (AA 1052)Boeing 737 800
      • American Airlines (AA 3272)
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      • 10:58 TYS
        14:12 ORD
        4Hrs, 14m 1 Stop (CLT)
      • TYSKnoxville Airport 10:58 - ORD 14:12 4h 14m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 10:58
        CLTCharlotte Airport 13:04
      • CLTCharlotte Airport 12:15
        ORDChicago O'Hare International Airport 14:12
      • 4h 14m (49m)
      • 1 Stop CLT · Charlotte 49m
      • American Airlines (AA 5016)Canadair Regional
        American Airlines (AA 1052)Boeing 737 800
      • American Airlines (AA 5016)
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        • -
      • 10:58 TYS
        14:12 ORD
        4Hrs, 14m 1 Stop (CLT)
      • TYSKnoxville Airport 10:58 - ORD 14:12 4h 14m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 10:58
        CLTCharlotte Airport 13:04
      • CLTCharlotte Airport 12:15
        ORDChicago O'Hare International Airport 14:12
      • 4h 14m (49m)
      • 1 Stop CLT · Charlotte 49m
      • American Airlines (AA 5453)Canadair Regional
        American Airlines (AA 1052)Boeing 737 800
      • American Airlines (AA 5453)
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      • 10:58 TYS
        14:12 ORD
        4Hrs, 14m 1 Stop (CLT)
      • TYSKnoxville Airport 10:58 - ORD 14:12 4h 14m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 10:58
        CLTCharlotte Airport 13:04
      • CLTCharlotte Airport 12:15
        ORDChicago O'Hare International Airport 14:12
      • 4h 14m (49m)
      • 1 Stop CLT · Charlotte 49m
      • American Airlines (AA 5580)Canadair Regional
        American Airlines (AA 1052)Boeing 737 800
      • American Airlines (AA 5580)
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      • 14:35 TYS
        18:55 ORD
        5Hrs, 20m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:55 5h 20m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:35
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:55
      • 5h 20m (1h 15m)
      • 1 Stop IAD · Washington 1h 15m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Airbus
      • United Airlines (UA 4848)
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        • -
      • 14:35 TYS
        18:42 ORD
        5Hrs, 07m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:42 5h 07m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:22
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:42
      • 5h 07m (1h 02m)
      • 1 Stop IAD · Washington 1h 02m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Airbus
      • United Airlines (UA 4848)
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      • 14:35 TYS
        18:49 ORD
        5Hrs, 14m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:49 5h 14m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:29
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:49
      • 5h 14m (1h 09m)
      • 1 Stop IAD · Washington 1h 09m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Boeing 737 900
      • United Airlines (UA 4848)
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      • 14:35 TYS
        18:42 ORD
        5Hrs, 07m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:42 5h 07m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:22
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:42
      • 5h 07m (1h 02m)
      • 1 Stop IAD · Washington 1h 02m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Boeing 737 900
      • United Airlines (UA 4848)
        • M
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      • 14:35 TYS
        18:55 ORD
        5Hrs, 20m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:55 5h 20m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:35
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:55
      • 5h 20m (1h 15m)
      • 1 Stop IAD · Washington 1h 15m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Boeing 737 900
      • United Airlines (UA 4848)
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      • 14:35 TYS
        18:42 ORD
        5Hrs, 07m 1 Stop (IAD)
      • TYSKnoxville Airport 14:35 - ORD 18:42 5h 07m 1 Stop (IAD) Washington
      • TYSKnoxville Airport 14:35
        IADWashington Dulles International Airport 17:22
      • IADWashington Dulles International Airport 16:20
        ORDChicago O'Hare International Airport 18:42
      • 5h 07m (1h 02m)
      • 1 Stop IAD · Washington 1h 02m
      • United Airlines (UA 4848)Embraer
        United Airlines (UA 2497)Airbus
      • United Airlines (UA 4848)
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        • -
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      • 14:38 TYS
        18:09 ORD
        4Hrs, 31m 1 Stop (CLT)
      • TYSKnoxville Airport 14:38 - ORD 18:09 4h 31m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 14:38
        CLTCharlotte Airport 16:58
      • CLTCharlotte Airport 15:57
        ORDChicago O'Hare International Airport 18:09
      • 4h 31m (1h 01m)
      • 1 Stop CLT · Charlotte 1h 01m
      • American Airlines (AA 5321)Canadair Regional
        American Airlines (AA 2569)Boeing 737 800
      • American Airlines (AA 5321)
        • -
        • -
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        • S
        • -
      • 14:38 TYS
        19:24 ORD
        5Hrs, 46m 1 Stop (CLT)
      • TYSKnoxville Airport 14:38 - ORD 19:24 5h 46m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 14:38
        CLTCharlotte Airport 18:16
      • CLTCharlotte Airport 15:57
        ORDChicago O'Hare International Airport 19:24
      • 5h 46m (2h 19m)
      • 1 Stop CLT · Charlotte 2h 19m
      • American Airlines (AA 5321)Canadair Regional
        American Airlines (AA 2488)Airbus
      • American Airlines (AA 5321)
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      • 14:38 TYS
        17:43 ORD
        4Hrs, 05m 1 Stop (CLT)
      • TYSKnoxville Airport 14:38 - ORD 17:43 4h 05m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 14:38
        CLTCharlotte Airport 16:38
      • CLTCharlotte Airport 15:57
        ORDChicago O'Hare International Airport 17:43
      • 4h 05m (41m)
      • 1 Stop CLT · Charlotte 41m
      • American Airlines (AA 5321)Canadair Regional
        American Airlines (AA 2569)Airbus
      • American Airlines (AA 5321)
        • M
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      • 16:07 TYS
        19:24 ORD
        4Hrs, 17m 1 Stop (CLT)
      • TYSKnoxville Airport 16:07 - ORD 19:24 4h 17m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 16:07
        CLTCharlotte Airport 18:16
      • CLTCharlotte Airport 17:27
        ORDChicago O'Hare International Airport 19:24
      • 4h 17m (49m)
      • 1 Stop CLT · Charlotte 49m
      • American Airlines (AA 5613)Crj 700 Canadair Regional
        American Airlines (AA 2488)Airbus
      • American Airlines (AA 5613)
        • M
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        • S
      • 16:07 TYS
        19:30 ORD
        4Hrs, 23m 1 Stop (CLT)
      • TYSKnoxville Airport 16:07 - ORD 19:30 4h 23m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 16:07
        CLTCharlotte Airport 18:16
      • CLTCharlotte Airport 17:27
        ORDChicago O'Hare International Airport 19:30
      • 4h 23m (49m)
      • 1 Stop CLT · Charlotte 49m
      • American Airlines (AA 5613)Crj 700 Canadair Regional
        American Airlines (AA 2488)Boeing 737 800
      • American Airlines (AA 5613)
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      • 17:58 TYS
        21:57 ORD
        4Hrs, 59m 1 Stop (CLT)
      • TYSKnoxville Airport 17:58 - ORD 21:57 4h 59m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 17:58
        CLTCharlotte Airport 20:45
      • CLTCharlotte Airport 19:20
        ORDChicago O'Hare International Airport 21:57
      • 4h 59m (1h 25m)
      • 1 Stop CLT · Charlotte 1h 25m
      • American Airlines (AA 5840)Er4 Embraer Rj145 Amazon
        American Airlines (AA 815)Airbus
      • American Airlines (AA 5840)
        • -
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        • -
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        • S
        • -
      • 18:01 TYS
        21:52 ORD
        4Hrs, 51m 1 Stop (CLT)
      • TYSKnoxville Airport 18:01 - ORD 21:52 4h 51m 1 Stop (CLT) Charlotte
      • TYSKnoxville Airport 18:01
        CLTCharlotte Airport 20:40
      • CLTCharlotte Airport 19:23
        ORDChicago O'Hare International Airport 21:52
      • 4h 51m (1h 17m)
      • 1 Stop CLT · Charlotte 1h 17m
      • American Airlines (AA 5840)Er4 Embraer Rj145 Amazon
        American Airlines (AA 815)Airbus
      • American Airlines (AA 5840)
        • M
        • -
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        • -
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      • 18:26 TYS
        22:58 ORD
        5Hrs, 32m 1 Stop (PHL)
      • TYSKnoxville Airport 18:26 - ORD 22:58 5h 32m 1 Stop (PHL) Philadelphia
      • TYSKnoxville Airport 18:26
        PHLPhiladelphia International Airport 21:20
      • PHLPhiladelphia International Airport 20:20
        ORDChicago O'Hare International Airport 22:58
      • 5h 32m (1h)
      • 1 Stop PHL · Philadelphia 1h
      • American Airlines (AA 5846)Er4 Embraer Rj145 Amazon
        American Airlines (AA 2095)Boeing 737 800
      • American Airlines (AA 5846)
        • M
        • -
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        • F
        • -
        • S
      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Knoxville to Chicago?

      The fastest flight time for direct flights from Knoxville to Chicago is 1 hour 55 minutes. Check latest flight schedules & prices on Wego.

      What’s the most popular airline flying from Knoxville to Chicago?

      The most popular airline flying from Knoxville to Chicago is American Airlines. Find the latest flight deals on Wego.

      How far is Chicago from Knoxville?

      The flight distance between Knoxville and Chicago is 732km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:00. The last flight of the day departs at 19:24. See the full list of flight times on Wego.

      How many airlines offer direct flights from Knoxville to Chicago?

      There are 2 airlines that offer direct flights from Knoxville to Chicago. Find out the list of airlines on Wego.

      All Airports in Knoxville

      Knoxville Airport TYS

      Popular Airlines Flying From Knoxville to Chicago

      American Airlines ‏()
      Allegiant Air LLC ‏()

      Popular Destinations From Chicago

      Popular Destinations From Knoxville

      Popular Hotels in Chicago

      Hotels In Popular Destinations